antigenic drift

antigenic drift of h_9n_2 subtype avian influenza viruses in henan province during 1998-2002

1998～2002年间河南省H9N2亚型AIV的抗原性漂变研究

results in april 2001 new antigenic drift strain a 3/ 112/ guizhou/ 2001/ was separated from influenza-like illness in guiyang.

结果2001年4月在贵阳类流感病人中分离出一株A3/112/GuiZhou/2001的新变异株。

objective to study pandemic type of influenza viruses in the human population and early discover new antigenic drift strain.

目的了解人群中流感流行的流感病毒型别，及时发现新的变异株。

objective to understand the epidemics and antigenic drift of influenza a ( h3n2) viruses in guangdong province in 2002. method influenzas viruses isolated were cultured in mdck cell and embryonated eggs.

目的了解广东省2002年H3N2亚型流感病毒流行及抗原性变异情况。

objective: understand influenza b viruses circulating and antigenic drift and distributing since 2003 in ningbo city.

目的：了解近年来宁波市乙型流行性感冒病毒流行和抗原性的变异情况及种系分布。

part of these changes are due to antigenic drift, alterations caused by spontaneous mutation, producing minor changes in the antigenic structure of hemagglutinin.

抗原漂流为血凝素抗原结构微小变异，抗原突变为病毒在自然界进行基因重组。

owing to error-prone polymerase and segmented genome of influenza virus, there is common phenomenon of mutations ( antigenic drift) and reassortment ( antigenic shift) for influenza virus and emergence of new variants or strains.

由于其易于出错的聚合酶和片断化基因，流感病毒基因突变（抗原漂移）、重配（抗原转移）而产生新病毒株的现象非常普遍。